Stability study of azithromycin in ophthalmic preparations
نویسندگان
چکیده
منابع مشابه
Anti-infective ophthalmic preparations in general practice
Ocular infections may be bacterial, viral, fungal or parasitic in aetiology. Pharmacological preparations are available to treat infections that are caused by these groups of organisms. The majority of these preparations are intended for topical administration, although some systemically administered agents may be needed to treat or prevent specific ocular infections. This article discusses the...
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Gelation of pectin caused by divalent cations especially calcium ions has been applied to develop an ophthalmic formulation of azithromycin in the present study. Rapid elimination of drug on instillation into cul de sac would be minimal with in situ gelling ophthalmic solution leading to increased precorneal contact time and prolonged drug delivery. In the formulation development studies pectin...
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Stability study of ceftazidime was realized in order to investigate kinetics of degradation of this drug both in powder for injection and reconstituted sample. Ceftazidime was submitted to conditions of accelerated thermal degradation and photodegradation. Analyses of the degraded samples were performed by microbiological assay and decomposition reactions could be described by zero-order and se...
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ژورنال
عنوان ژورنال: Brazilian Journal of Pharmaceutical Sciences
سال: 2009
ISSN: 1984-8250
DOI: 10.1590/s1984-82502009000200005